Apps/Biotech

Cheap ligand that pulls antibodies out of cell broth

WhyCategoryBiotech
LevelHard
UseReplace costly Protein A resin, the biggest consumable in antibody manufacturing
WhatAtomsAntibody binding patch 1–3k + ligand 20–60 + water. C H O N S
BuildTestingMedium Resin binding and release tests
FundingCompute ~$300 · Make ~$10–30k · Test ~$30–80k resin tests · Other ~$20k patents
TimeMake 2–3 months · Test 4–8 wks · Total ~3–5 months
HowContact us for the design specs and build plan →
DemoLigand grips the antibody’s stem, then lets go when pH drops
CompetitionProtein A resins (Cytiva MabSelect, Repligen), mimetic ligands (MEP HyperCel)
BusinessBuyersCytiva, Repligen, Merck, antibody makers
RevenueVery high License to resin makers. ~$5–20M/yr if adopted
MEP, a simple antibody-capture ligand